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    tomm-22 Mitochondrial import receptor subunit TOM22 homolog [ Caenorhabditis elegans ]

    Gene ID: 173436, updated on 9-Dec-2024

    Summary

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    Official Symbol
    tomm-22
    Official Full Name
    Mitochondrial import receptor subunit TOM22 homolog
    Primary source
    WormBase:WBGene00021133
    Locus tag
    CELE_W10D9.5
    See related
    AllianceGenome:WB:WBGene00021133
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in intracellular protein transport. Predicted to be located in mitochondrial outer membrane. Orthologous to human TOMM22 (translocase of outer mitochondrial membrane 22). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See tomm-22 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    2
    Sequence:
    Chromosome: II; NC_003280.10 (468374..470475, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene MKRN2 opposite strand protein-like C-terminal domain-containing protein Neighboring gene Nuclear transcription factor Y subunit nfyb-1 Neighboring gene ncRNA Neighboring gene 26S rRNA (cytosine-C(5))-methyltransferase nsun-1 Neighboring gene G_PROTEIN_RECEP_F2_4 domain-containing protein Neighboring gene NLE domain-containing protein;WD_REPEATS_REGION domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The evolutionarily conserved ESRE stress response network is activated by ROS and mitochondrial damage. Tjahjono E, et al. BMC Biol, 2020 Jun 29. PMID 32600387, Free PMC Article
    2. A modified TurboID approach identifies tissue-specific centriolar components in C. elegans. Holzer E, et al. PLoS Genet, 2022 Apr. PMID 35442950, Free PMC Article
    3. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    4. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    5. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrial outer membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Mitochondrial import receptor subunit TOM22 homolog
    NP_001368584.1
    • Confirmed by transcript evidence
    NP_493741.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      468374..470475 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_061340.6 → NP_493741.1  Mitochondrial import receptor subunit TOM22 homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_493741.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0A0M7RDR0, O17287
      Conserved Domains (1) summary
      cl11522
      Location:6 → 92
      Tom22; Mitochondrial import receptor subunit Tom22

    2. NM_001381316.1 → NP_001368584.1  Mitochondrial import receptor subunit TOM22 homolog [Caenorhabditis elegans]

      Status: REVIEWED

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O17287.1

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