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    ceh-91 Homeobox domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 176594, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ceh-91
    Official Full Name
    Homeobox domain-containing protein
    Primary source
    WormBase:WBGene00013425
    Locus tag
    CELE_Y66A7A.5
    See related
    AllianceGenome:WB:WBGene00013425
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable DNA binding activity and chromatin binding activity. Predicted to be involved in negative regulation of gene expression, epigenetic. Predicted to be active in nucleus. Is expressed in head muscle; intestine; nervous system; and rectal gland cell. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ceh-91 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    8
    Sequence:
    Chromosome: III; NC_003281.10 (11616746..11623994)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Transposase Neighboring gene Neuropeptide-Like Protein Neighboring gene Aminotran_5 domain-containing protein Neighboring gene putative N-acetylgalactosaminyltransferase 8 Neighboring gene IMV envelope protein Neighboring gene Putative T-box protein 33

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Unique homeobox codes delineate all the neuron classes of C. elegans. Reilly MB, et al. Nature, 2020 Aug. PMID 32814896, Free PMC Article
    2. Extensive rewiring and complex evolutionary dynamics in a C. elegans multiparameter transcription factor network. Reece-Hoyes JS, et al. Mol Cell, 2013 Jul 11. PMID 23791784, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in negative regulation of gene expression, epigenetic IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Homeobox domain-containing protein
    NP_499503.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      11616746..11623994
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_067102.5 → NP_499503.2  Homeobox domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_499503.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7K6J1
      Conserved Domains (1) summary
      cd00086
      Location:525 → 582
      homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
    Nucleotide Protein
    Heading Accession and Version

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