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    F54A3.5 MICOS complex subunit Mic10 [ Caenorhabditis elegans ]

    Gene ID: 173579, updated on 9-Dec-2024

    Summary

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    Official Symbol
    F54A3.5
    Official Full Name
    MICOS complex subunit Mic10
    Primary source
    WormBase:WBGene00018784
    Locus tag
    CELE_F54A3.5
    See related
    AllianceGenome:WB:WBGene00018784
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be located in mitochondrial inner membrane. Predicted to be part of MICOS complex. Predicted to be active in mitochondrion. Orthologous to human MICOS10 (mitochondrial contact site and cristae organizing system subunit 10). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See F54A3.5 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    2
    Sequence:
    Chromosome: II; NC_003280.10 (2224359..2225708, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Trichohyalin Neighboring gene ncRNA Neighboring gene Putative cystathionine beta-synthase cbs-2 Neighboring gene Periphilin-1-like;Trithorax group protein osa Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Trifunctional cross-linker for mapping protein-protein interaction networks and comparing protein conformational states. Tan D, et al. Elife, 2016 Mar 8. PMID 26952210, Free PMC Article
    2. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
    3. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    part_of MICOS complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    MICOS complex subunit Mic10
    NP_494216.1
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      2224359..2225708 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_061815.6 → NP_494216.1  MICOS complex subunit Mic10 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_494216.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9N4K0
      Conserved Domains (1) summary
      pfam04418
      Location:12 → 73
      DUF543; Domain of unknown function (DUF543)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9N4K0.2

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