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    kdp-1 KASH (Klarsicht/ANC-1/Syne Homology) Domain Protein [ Caenorhabditis elegans ]

    Gene ID: 178288, updated on 9-Dec-2024

    Summary

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    Official Symbol
    kdp-1
    Official Full Name
    KASH (Klarsicht/ANC-1/Syne Homology) Domain Protein
    Primary source
    WormBase:WBGene00013463
    Locus tag
    CELE_Y67H2A.5
    See related
    AllianceGenome:WB:WBGene00013463
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Located in cytoplasm and nuclear envelope. Used to study muscular dystrophy. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See kdp-1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_003282.8 (13300188..13300625)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Kelch domain-containing protein 10 Neighboring gene Calcium uptake protein 1 homolog, mitochondrial Neighboring gene COP9 signalosome complex subunit 6 Neighboring gene Peptidase M3A/M3B catalytic domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. KDP-1 is a nuclear envelope KASH protein required for cell-cycle progression. McGee MD, et al. J Cell Sci, 2009 Aug 15. PMID 19638405, Free PMC Article
    2. TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM. Couillault C, et al. Nat Immunol, 2004 May. PMID 15048112
    3. SAFER, an Analysis Method of Quantitative Proteomic Data, Reveals New Interactors of the C. elegans Autophagic Protein LGG-1. Yi Z, et al. J Proteome Res, 2016 May 6. PMID 26999449
    4. Determining the sub-cellular localization of proteins within Caenorhabditis elegans body wall muscle. Meissner B, et al. PLoS One, 2011. PMID 21611156, Free PMC Article
    5. CCAR-1 works together with the U2AF large subunit UAF-1 to regulate alternative splicing. Lugano DI, et al. RNA Biol, 2024 Jan. PMID 38126797, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion HDA PubMed 
    located_in nuclear envelope IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    KASH (Klarsicht/ANC-1/Syne Homology) Domain Protein
    NP_502556.1
    • Product from WormBase gene class kdp;
      Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      13300188..13300625
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_070155.6 → NP_502556.1  KASH (Klarsicht/ANC-1/Syne Homology) Domain Protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_502556.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95PZ1
    Nucleotide Protein
    Heading Accession and Version

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