ubl-5 Ubiquitin-like protein 5 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: ubl-5
Official Full Name: Ubiquitin-like protein 5
Primary source: WormBase:WBGene00006726
Locus tag: CELE_F46F11.4
See related: AllianceGenome:WB:WBGene00006726
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable protein tag activity. Involved in mitochondrial unfolded protein response and positive regulation of gene expression. Located in cytosol and nucleus. Part of transcription regulator complex. Is expressed in intestine and pharynx. Orthologous to human UBL5 (ubiquitin like 5). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See ubl-5 in Genome Data Viewer

Location:: chromosome: I

Exon count:: 2

Sequence:: Chromosome: I; NC_003279.8 (5607826..5608841, complement)

Chromosome I - NC_003279.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The ubiquitin-like protein Hub1/UBL-5 functions in pre-mRNA splicing in Caenorhabditis elegans.
Title: The ubiquitin-like protein Hub1/UBL-5 functions in pre-mRNA splicing in Caenorhabditis elegans.

Submit: New GeneRIF Correction

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

F46F11.4 (e-PCR)
- UniSTS:315817

F46F11.5 (e-PCR)
- UniSTS:315818

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables protein tag activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in mRNA splicing, via spliceosome	IBA Inferred from Biological aspect of Ancestor more info
involved_in mitochondrial unfolded protein response	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of gene expression	IGI Inferred from Genetic Interaction more info	PubMed
involved_in protein modification process	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein modification process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytosol	IDA Inferred from Direct Assay more info	PubMed
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
part_of transcription regulator complex	IPI Inferred from Physical Interaction more info	PubMed

General protein information

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Preferred Names: Ubiquitin-like protein 5

NP_491640.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003279.8 Reference assembly

Range

5607826..5608841 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_059239.6 → NP_491640.1 Ubiquitin-like protein 5 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_491640.1

Status: REVIEWED

UniProtKB/Swiss-Prot

P91302

Conserved Domains (1) summary

cd01791
Location:1 → 73

Ubl5; UBL5 ubiquitin-like modifier