die-1 C2H2-type domain-containing protein [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: die-1
Official Full Name: C2H2-type domain-containing protein
Primary source: WormBase:WBGene00000995
Locus tag: CELE_C18D1.1
See related: AllianceGenome:WB:WBGene00000995
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Involved in several processes, including cell fate specification; maintenance of left/right asymmetry; and neuron development involved in amphid sensory organ development. Is expressed in several structures, including amphid neurons; head; intestine; oocyte; and somatic nervous system. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See die-1 in Genome Data Viewer

Location:: chromosome: II

Exon count:: 6

Sequence:: Chromosome: II; NC_003280.10 (10061302..10067917, complement)

Chromosome II - NC_003280.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

die-1 is expressed in a directionally asymmetric manner in the gustatory neuron pair ASE left (ASEL) and ASE right (ASER), while it is expressed in an antisymmetric manner in the olfactory neuron pair AWC left (AWCL) and AWC right (AWCR)
Title: Two distinct types of neuronal asymmetries are controlled by the Caenorhabditis elegans zinc finger transcription factor die-1.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

C18D1.1 (e-PCR)
- UniSTS:307265

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Process	Evidence Code	Pubs
involved_in cell fate specification	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in maintenance of left/right asymmetry	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in neuron development involved in amphid sensory organ development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of gene expression	IGI Inferred from Genetic Interaction more info	PubMed
involved_in positive regulation of gene expression	IMP Inferred from Mutant Phenotype more info	PubMed

General protein information

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Preferred Names: C2H2-type domain-containing protein

NP_001309538.1

Confirmed by transcript evidence

NP_496175.2

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003280.10 Reference assembly

Range

10061302..10067917 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_063774.8 → NP_496175.2 C2H2-type domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

A0A131MCL4
NM_001322752.3 → NP_001309538.1 C2H2-type domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

A0A131MCR4