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    rfk-1 riboflavin kinase [ Caenorhabditis elegans ]

    Gene ID: 187789, updated on 9-Dec-2024

    Summary

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    Official Symbol
    rfk-1
    Official Full Name
    riboflavin kinase
    Primary source
    WormBase:WBGene00011224
    Locus tag
    CELE_R10H10.6
    See related
    AllianceGenome:WB:WBGene00011224
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable riboflavin kinase activity. Predicted to be involved in FMN biosynthetic process and riboflavin metabolic process. Predicted to be active in mitochondrion. Orthologous to human RFK (riboflavin kinase). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See rfk-1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    2
    Sequence:
    Chromosome: IV; NC_003282.8 (10408703..10409477, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene CUB domain-containing protein Neighboring gene ncRNA Neighboring gene DUF3149 domain-containing protein Neighboring gene Guanine nucleotide-binding protein alpha-7 subunit Neighboring gene Non-specific serine/threonine protein kinase Neighboring gene SH2 domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    2. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables riboflavin kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables riboflavin kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in FMN biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in FMN biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in riboflavin biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in riboflavin metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    riboflavin kinase
    NP_501922.1
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      10408703..10409477 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_069521.2 → NP_501922.1  riboflavin kinase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_501922.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q21918
      Conserved Domains (1) summary
      pfam01687
      Location:5 → 127
      Flavokinase; Riboflavin kinase
    Nucleotide Protein
    Heading Accession and Version

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