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    K10C3.5 Tr-type G domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 172838, updated on 9-Dec-2024

    Summary

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    Official Symbol
    K10C3.5
    Official Full Name
    Tr-type G domain-containing protein
    Primary source
    WormBase:WBGene00010732
    Locus tag
    CELE_K10C3.5
    See related
    AllianceGenome:WB:WBGene00010732
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable GTPase activity and ribosome binding activity. Predicted to be involved in cytosolic ribosome assembly. Predicted to be part of ribonucleoprotein complex. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in Shwachman-Diamond syndrome. Orthologous to human EFL1 (elongation factor like GTPase 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See K10C3.5 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    6
    Sequence:
    Chromosome: I; NC_003279.8 (9863584..9869064)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Transmembrane protein 98 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene NR LBD domain-containing protein;Nuclear hormone receptor family member nhr-49 Neighboring gene Innexin Neighboring gene Nuclear hormone receptor family member nhr-69

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ribosome binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytosolic ribosome assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of ribonucleoprotein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Tr-type G domain-containing protein
    NP_001021564.1
    • Confirmed by transcript evidence
    NP_001021565.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      9863584..9869064
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001026394.4 → NP_001021565.1  Tr-type G domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001021565.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q564S2
      Conserved Domains (1) summary
      cl30786
      Location:18 → 685
      FusA; Translation elongation factor EF-G, a GTPase [Translation, ribosomal structure and biogenesis]

    2. NM_001026393.4 → NP_001021564.1  Tr-type G domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001021564.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O17944
      Conserved Domains (1) summary
      cl30786
      Location:18 → 874
      FusA; Translation elongation factor EF-G, a GTPase [Translation, ribosomal structure and biogenesis]
    Nucleotide Protein
    Heading Accession and Version

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