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    alh-10 Aldehyde dehydrogenase domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 180979, updated on 9-Dec-2024

    Summary

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    Official Symbol
    alh-10
    Official Full Name
    Aldehyde dehydrogenase domain-containing protein
    Primary source
    WormBase:WBGene00000116
    Locus tag
    CELE_C54D1.4
    See related
    AllianceGenome:WB:WBGene00000116
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor. Is expressed in intestine and nervous system. Orthologous to human ALDH8A1 (aldehyde dehydrogenase 8 family member A1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See alh-10 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    9
    Sequence:
    Chromosome: X; NC_003284.9 (7140504..7143641, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene HEsitatioN behavior Neighboring gene IRS-type PTB domain-containing protein Neighboring gene ncRNA Neighboring gene C-type lectin domain-containing protein Neighboring gene Laminin-like protein lam-2 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Fat accumulation in Caenorhabditis elegans triggered by the electrophilic lipid peroxidation product 4-hydroxynonenal (4-HNE). Singh SP, et al. Aging (Albany NY), 2008 Dec 18. PMID 20157589, Free PMC Article
    2. Comparative genomics and functional study of lipid metabolic genes in Caenorhabditis elegans. Zhang Y, et al. BMC Genomics, 2013 Mar 12. PMID 23496871, Free PMC Article
    3. Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans. Artan M, et al. J Biol Chem, 2022 Sep. PMID 35933017, Free PMC Article
    4. Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling. Artan M, et al. J Biol Chem, 2021 Sep. PMID 34416233, Free PMC Article
    5. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Aldehyde dehydrogenase domain-containing protein
    NP_509203.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      7140504..7143641 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_076802.5 → NP_509203.1  Aldehyde dehydrogenase domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_509203.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q18822
      Conserved Domains (1) summary
      cd07093
      Location:45 → 500
      ALDH_F8_HMSADH; Human aldehyde dehydrogenase family 8 member A1-like
    Nucleotide Protein
    Heading Accession and Version

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