clec-86 C-type lectin domain-containing protein [Caenorhabditis elegans] - Gene

Summary

Official Symbol: clec-86
Official Full Name: C-type lectin domain-containing protein
Primary source: WormBase:WBGene00016912
Locus tag: CELE_C54D1.2
See related: AllianceGenome:WB:WBGene00016912
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable carbohydrate binding activity and pattern recognition receptor activity. Involved in innate immune response. Predicted to be active in external side of plasma membrane. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to human REG1A (regenerating family member 1 alpha); REG1B (regenerating family member 1 beta); and REG3G (regenerating family member 3 gamma). [provided by Alliance of Genome Resources, Dec 2024]
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Chromosome X - NC_003284.9 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables carbohydrate binding	IBA Inferred from Biological aspect of Ancestor more info
enables pattern recognition receptor activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in immune response	IBA Inferred from Biological aspect of Ancestor more info
involved_in innate immune response	HEP more info	PubMed

Component	Evidence Code	Pubs
is_active_in external side of plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

NP_509202.1

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