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    fkh-5 Putative forkhead-related transcription factor fkh-5 [ Caenorhabditis elegans ]

    Gene ID: 184944, updated on 9-Dec-2024

    Summary

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    Official Symbol
    fkh-5
    Official Full Name
    Putative forkhead-related transcription factor fkh-5
    Primary source
    WormBase:WBGene00001437
    Locus tag
    CELE_F26A1.2
    See related
    AllianceGenome:WB:WBGene00001437
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be active in nucleus. Is expressed in head neurons. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See fkh-5 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    3
    Sequence:
    Chromosome: III; NC_003281.10 (4844662..4846608)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene ACB domain-containing protein Neighboring gene C-type lectin domain-containing protein Neighboring gene C-type lectin domain-containing protein Neighboring gene Smr domain-containing protein Neighboring gene Non-structural maintenance of chromosomes element 4 Neighboring gene Cell death protein 4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Promoters recognized by forkhead proteins exist for individual 21U-RNAs. Cecere G, et al. Mol Cell, 2012 Sep 14. PMID 22819322, Free PMC Article
    2. The forkhead gene family of Caenorhabditis elegans. Hope IA, et al. Gene, 2003 Jan 30. PMID 12568714
    3. PHA-4/Foxa mediates diet-restriction-induced longevity of C. elegans. Panowski SH, et al. Nature, 2007 May 31. PMID 17476212
    4. TGF-beta signaling. Savage-Dunn C. WormBook, 2005 Sep 9. PMID 18050404, Free PMC Article
    5. A global analysis of genetic interactions in Caenorhabditis elegans. Byrne AB, et al. J Biol, 2007. PMID 17897480, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Putative forkhead-related transcription factor fkh-5
    NP_498003.2
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      4844662..4846608
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_065602.3 → NP_498003.2  Putative forkhead-related transcription factor fkh-5 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_498003.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q19802
      Conserved Domains (1) summary
      smart00339
      Location:172 → 260
      FH; FORKHEAD
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q19802.2

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