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    snx-13 PX domain-containing protein;PXA domain-containing protein;Sorting nexin-13 [ Caenorhabditis elegans ]

    Gene ID: 178482, updated on 9-Dec-2024

    Summary

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    Official Symbol
    snx-13
    Official Full Name
    PX domain-containing protein;PXA domain-containing protein;Sorting nexin-13
    Primary source
    WormBase:WBGene00013803
    Locus tag
    CELE_Y116A8C.26
    See related
    AllianceGenome:WB:WBGene00013803
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable phosphatidylinositol binding activity. Predicted to be located in membrane. Predicted to be active in early endosome. Orthologous to human SNX13 (sorting nexin 13). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See snx-13 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    14
    Sequence:
    Chromosome: IV; NC_003282.8 (17078820..17087438, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene protein-ribulosamine 3-kinase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Lipoprotein;Recep_L_domain domain-containing protein Neighboring gene Small nuclear ribonucleoprotein Sm D3 Neighboring gene ATP synthase mitochondrial F1 complex assembly factor 2;DUF3800 domain-containing protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. SNX-3 mediates retromer-independent tubular endosomal recycling by opposing EEA-1-facilitated trafficking. Tian Y, et al. PLoS Genet, 2021 Jun. PMID 34081703, Free PMC Article
    2. A pathway for phagosome maturation during engulfment of apoptotic cells. Kinchen JM, et al. Nat Cell Biol, 2008 May. PMID 18425118, Free PMC Article
    3. RNA targets and specificity of Staufen, a double-stranded RNA-binding protein in Caenorhabditis elegans. LeGendre JB, et al. J Biol Chem, 2013 Jan 25. PMID 23195953, Free PMC Article
    4. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables phosphatidylinositol binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phosphatidylinositol binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in early endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    PX domain-containing protein;PXA domain-containing protein;Sorting nexin-13
    NP_001255919.1
    • Confirmed by transcript evidence
    NP_001299974.1
    • Confirmed by transcript evidence
    NP_001359711.1
    • Confirmed by transcript evidence
    NP_503026.3
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      17078820..17087438 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_070625.8 → NP_503026.3  Sorting nexin-13 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_503026.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9U2U6
      Conserved Domains (4) summary
      cd08719
      Location:380 → 510
      RGS_SNX13; Regulator of G protein signaling (RGS) domain found in the Sorting Nexin 13 (SNX13) protein
      pfam02194
      Location:95 → 283
      PXA; PXA domain
      pfam08628
      Location:791 → 899
      Nexin_C; Sorting nexin C terminal
      cl02563
      Location:564 → 683
      PX_domain; The Phox Homology domain, a phosphoinositide binding module

    2. NM_001313045.3 → NP_001299974.1  Sorting nexin-13 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0K3AUG5
      Conserved Domains (3) summary
      cd08719
      Location:61 → 191
      RGS_SNX13; Regulator of G protein signaling (RGS) domain found in the Sorting Nexin 13 (SNX13) protein
      pfam08628
      Location:472 → 580
      Nexin_C; Sorting nexin C terminal
      cl02563
      Location:245 → 364
      PX_domain; The Phox Homology domain, a phosphoinositide binding module

    3. NM_001268990.3 → NP_001255919.1  PX domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255919.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H1UBK0
      Conserved Domains (3) summary
      pfam08628
      Location:372 → 480
      Nexin_C; Sorting nexin C terminal
      cl02563
      Location:145 → 264
      PX_domain; The Phox Homology domain, a phosphoinositide binding module
      cl02565
      Location:7 → 91
      RGS; Regulator of G protein signaling (RGS) domain superfamily

    4. NM_001372974.2 → NP_001359711.1  PXA domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A5HWB0
      Conserved Domains (1) summary
      pfam02194
      Location:94 → 143
      PXA; PXA domain
    Nucleotide Protein
    Heading Accession and Version

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