eef-1B.1 putative elongation factor 1-beta/1-delta 1 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: eef-1B.1
Official Full Name: putative elongation factor 1-beta/1-delta 1
Primary source: WormBase:WBGene00018846
Locus tag: CELE_F54H12.6
See related: AllianceGenome:WB:WBGene00018846
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in translational elongation. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic translation elongation factor 1 complex. Predicted to be active in cytosol. Orthologous to human EEF1B2 (eukaryotic translation elongation factor 1 beta 2). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See eef-1B.1 in Genome Data Viewer

Location:: chromosome: III

Exon count:: 3

Sequence:: Chromosome: III; NC_003281.10 (7972382..7973386, complement)

Chromosome III - NC_003281.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

F54H12.6 (e-PCR)
- UniSTS:320991

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables guanyl-nucleotide exchange factor activity	IBA Inferred from Biological aspect of Ancestor more info
enables translation elongation factor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in translation	IEA Inferred from Electronic Annotation more info
involved_in translational elongation	IBA Inferred from Biological aspect of Ancestor more info
involved_in translational elongation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
part_of eukaryotic translation elongation factor 1 complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: putative elongation factor 1-beta/1-delta 1

NP_498737.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003281.10 Reference assembly

Range

7972382..7973386 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_066336.8 → NP_498737.1 putative elongation factor 1-beta/1-delta 1 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_498737.1

Status: REVIEWED

UniProtKB/Swiss-Prot

P34460

Conserved Domains (3) summary

pfam00736
Location:129 → 213

EF1_GNE; EF-1 guanine nucleotide exchange domain

pfam10587
Location:90 → 110

EF-1_beta_acid; Eukaryotic elongation factor 1 beta central acidic region

cl02776
Location:1 → 62

GST_C_family; C-terminal, alpha helical domain of the Glutathione S-transferase family