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    grd-3 Ground-like domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 177109, updated on 9-Dec-2024

    Summary

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    Official Symbol
    grd-3
    Official Full Name
    Ground-like domain-containing protein
    Primary source
    WormBase:WBGene00001692
    Locus tag
    CELE_W05E7.1
    See related
    AllianceGenome:WB:WBGene00001692
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable signaling receptor binding activity. Involved in defense response to Gram-negative bacterium. Predicted to be located in extracellular region. Is expressed in hypodermis. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See grd-3 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    3
    Sequence:
    Chromosome: IV; NC_003282.8 (3439655..3440453)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Serpentine Receptor, class Z Neighboring gene GRounDhog (hedgehog-like family) Neighboring gene Ground-like domain-containing protein Neighboring gene Peptidase_M13_N domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Inducible antibacterial defense system in C. elegans. Mallo GV, et al. Curr Biol, 2002 Jul 23. PMID 12176330
    2. Identification of the hydrophobic glycoproteins of Caenorhabditis elegans. Fan X, et al. Glycobiology, 2005 Oct. PMID 15888633
    3. Caenorhabditis elegans has scores of hedgehog-related genes: sequence and expression analysis. Aspöck G, et al. Genome Res, 1999 Oct. PMID 10523520
    4. Comprehensive analysis of gene expression patterns of hedgehog-related genes. Hao L, et al. BMC Genomics, 2006 Oct 31. PMID 17076889, Free PMC Article
    5. The function and expansion of the Patched- and Hedgehog-related homologs in C. elegans. Zugasti O, et al. Genome Res, 2005 Oct. PMID 16204193, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables signaling receptor binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell-cell signaling ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in defense response to Gram-negative bacterium IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Ground-like domain-containing protein
    NP_500346.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      3439655..3440453
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_067945.6 → NP_500346.2  Ground-like domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_500346.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9TYW7
      Conserved Domains (1) summary
      pfam04155
      Location:36 → 115
      Ground-like; Ground-like domain
    Nucleotide Protein
    Heading Accession and Version

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