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    sym-3 C2 NT-type domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 183819, updated on 9-Dec-2024

    Summary

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    Official Symbol
    sym-3
    Official Full Name
    C2 NT-type domain-containing protein
    Primary source
    WormBase:WBGene00006368
    Locus tag
    CELE_C54H2.1
    See related
    AllianceGenome:WB:WBGene00006368
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Orthologous to human EEIG2 (EEIG family member 2) and EEIG1 (estrogen-induced osteoclastogenesis regulator 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See sym-3 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    7
    Sequence:
    Chromosome: X; NC_003284.9 (5776251..5778878)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene Surfeit locus protein 4 homolog Neighboring gene Protein kinase domain-containing protein Neighboring gene ZP domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. FBN-1, a fibrillin-related protein, is required for resistance of the epidermis to mechanical deformation during C. elegans embryogenesis. Kelley M, et al. Elife, 2015 Mar 23. PMID 25798732, Free PMC Article
    2. Effectors of anterior morphogenesis in C. elegans embryos. Balasubramaniam B, et al. Biol Open, 2023 Jul 15. PMID 37345480, Free PMC Article
    3. Combining Human Epigenetics and Sleep Studies in Caenorhabditis elegans: A Cross-Species Approach for Finding Conserved Genes Regulating Sleep. Huang H, et al. Sleep, 2017 Jun 1. PMID 28431118, Free PMC Article
    4. The identities of sym-2, sym-3 and sym-4, three genes that are synthetically lethal with mec-8 in Caenorhabditis elegans. Yochem J, et al. Genetics, 2004 Nov. PMID 15579686, Free PMC Article
    5. Functional overlap between the mec-8 gene and five sym genes in Caenorhabditis elegans. Davies AG, et al. Genetics, 1999 Sep. PMID 10471705, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    C2 NT-type domain-containing protein
    NP_001024500.1
    • Confirmed by transcript evidence
    NP_001024501.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      5776251..5778878
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001029329.8 → NP_001024500.1  C2 NT-type domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001024500.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q86GI2
      Conserved Domains (2) summary
      pfam10358
      Location:5 → 152
      NT-C2; N-terminal C2 in EEIG1 and EHBP1 proteins
      cl23717
      Location:224 → 275
      crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...

    2. NM_001029330.3 → NP_001024501.1  C2 NT-type domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001024501.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EE38
      Conserved Domains (1) summary
      pfam10358
      Location:5 → 152
      NT-C2; N-terminal C2 in EEIG1 and EHBP1 proteins
    Nucleotide Protein
    Heading Accession and Version

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