Y50D4C.3 Survival of motor neuron-related-splicing factor 30;Tudor domain-containing protein [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: Y50D4C.3
Official Full Name: Survival of motor neuron-related-splicing factor 30;Tudor domain-containing protein
Primary source: WormBase:WBGene00021748
Locus tag: CELE_Y50D4C.3
See related: AllianceGenome:WB:WBGene00021748
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable RNA binding activity. Predicted to be involved in RNA splicing and mRNA processing. Predicted to be located in cytoplasm and nuclear speck. Predicted to be part of spliceosomal complex. Predicted to be active in nucleus. Orthologous to human TDRD3 (tudor domain containing 3). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See Y50D4C.3 in Genome Data Viewer

Location:: chromosome: V

Exon count:: 5

Sequence:: Chromosome: V; NC_003283.11 (939391..945244, complement)

Chromosome V - NC_003283.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

Y50D4C_15.a (e-PCR)
- UniSTS:324384

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in RNA splicing	IEA Inferred from Electronic Annotation more info
involved_in mRNA processing	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in nuclear speck	IEA Inferred from Electronic Annotation more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
part_of spliceosomal complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Survival of motor neuron-related-splicing factor 30;Tudor domain-containing protein

NP_001300278.1

Confirmed by transcript evidence

NP_503358.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003283.11 Reference assembly

Range

939391..945244 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_070957.4 → NP_503358.1 Survival of motor neuron-related-splicing factor 30 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_503358.1

Status: REVIEWED

UniProtKB/TrEMBL

Q965Q9

Conserved Domains (3) summary

cd04508
Location:558 → 602

TUDOR; Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to ...

PRK12678
Location:343 → 482

PRK12678; transcription termination factor Rho; Provisional

pfam08585
Location:36 → 163

RMI1_N; RecQ mediated genome instability protein
NM_001313349.3 → NP_001300278.1 Tudor domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

A0A0K3AW48

Conserved Domains (1) summary

cd04508
Location:28 → 72

TUDOR; Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to ...