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    Y69A2AR.32 K Homology domain-containing protein;KH domain-containing protein;Protein kinase domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 177042, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Y69A2AR.32
    Official Full Name
    K Homology domain-containing protein;KH domain-containing protein;Protein kinase domain-containing protein
    Primary source
    WormBase:WBGene00022101
    Locus tag
    CELE_Y69A2AR.32
    See related
    AllianceGenome:WB:WBGene00022101
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable mRNA binding activity. Predicted to be involved in regulation of mRNA splicing, via spliceosome. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Y69A2AR.32 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    8
    Sequence:
    Chromosome: IV; NC_003282.8 (2610436..2612441)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Autophagy-related protein 101 Neighboring gene V-SNARE coiled-coil homology domain-containing protein Neighboring gene PEST proteolytic signal-containing nuclear protein Neighboring gene ncRNA Neighboring gene D-amino-acid oxidase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    K Homology domain-containing protein;KH domain-containing protein;Protein kinase domain-containing protein
    NP_001368328.1
    • Confirmed by transcript evidence
    NP_741340.2
    • Confirmed by transcript evidence
    NP_741341.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      2610436..2612441
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_171289.6 → NP_741340.2  K Homology domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_741340.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2L0S1
      Conserved Domains (1) summary
      cd02395
      Location:72 → 206
      SF1_like-KH; Splicing factor 1 (SF1) K homology RNA-binding domain (KH). Splicing factor 1 (SF1) specifically recognizes the intron branch point sequence (BPS) UACUAAC in the pre-mRNA transcripts during spliceosome assembly. We show that the KH-QUA2 region of SF1 ...

    2. NM_171290.6 → NP_741341.2  Protein kinase domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_741341.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T871
      Conserved Domains (1) summary
      cl00098
      Location:1 → 38
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...

    3. NM_001380098.1 → NP_001368328.1  KH domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      U4PCF9
      Conserved Domains (1) summary
      COG5178
      Location:20 → 48
      PRP8; U5 snRNP spliceosome subunit [RNA processing and modification]
    Nucleotide Protein
    Heading Accession and Version

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