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    zip-4 Transcription factor zip-4 [ Caenorhabditis elegans ]

    Gene ID: 171900, updated on 9-Dec-2024

    Summary

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    Official Symbol
    zip-4
    Official Full Name
    Transcription factor zip-4
    Primary source
    WormBase:WBGene00021552
    Locus tag
    CELE_Y44E3B.1
    See related
    AllianceGenome:WB:WBGene00021552
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in defense response to Gram-negative bacterium. Predicted to be located in nucleus. Is expressed in gonad; pharynx; and vulva. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See zip-4 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    4
    Sequence:
    Chromosome: I; NC_003279.8 (3264111..3266762, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Tyrosinase copper-binding domain-containing protein Neighboring gene Nop domain-containing protein Neighboring gene Prion-like-(Q/N-rich)-domain-bearing protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A conserved mitochondrial surveillance pathway is required for defense against Pseudomonas aeruginosa. Tjahjono E, et al. PLoS Genet, 2017 Jun. PMID 28662060, Free PMC Article
    2. Networks of bZIP protein-protein interactions diversified over a billion years of evolution. Reinke AW, et al. Science, 2013 May 10. PMID 23661758, Free PMC Article
    3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in defense response to Gram-negative bacterium IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Transcription factor zip-4
    NP_001040703.1
    • Confirmed by transcript evidence
    NP_001368002.1
    • Confirmed by transcript evidence
    NP_491133.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      3264111..3266762 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001381600.2 → NP_001368002.1  Transcription factor zip-4 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      G4SR45, H2L0N3, Q965I4
      Conserved Domains (2) summary
      cd14686
      Location:231 → 294
      bZIP; coiled coil [structural motif]
      cl21462
      Location:231 → 294
      bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain

    2. NM_058732.5 → NP_491133.1  Transcription factor zip-4 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491133.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q965I4
      Conserved Domains (2) summary
      cd14686
      Location:231 → 294
      bZIP; coiled coil [structural motif]
      cl21462
      Location:231 → 294
      bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain

    3. NM_001047238.7 → NP_001040703.1  Transcription factor zip-4 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001040703.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G4SR45
      Conserved Domains (2) summary
      cd14686
      Location:168 → 231
      bZIP; coiled coil [structural motif]
      cl21462
      Location:168 → 231
      bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    H2L0N3.1

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