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    rpb-7 DNA-directed RNA polymerase II subunit RPB7 [ Caenorhabditis elegans ]

    Gene ID: 171877, updated on 9-Dec-2024

    Summary

    Official Symbol
    rpb-7
    Official Full Name
    DNA-directed RNA polymerase II subunit RPB7
    Primary source
    WormBase:WBGene00021845
    Locus tag
    CELE_Y54E10BR.6
    See related
    AllianceGenome:WB:WBGene00021845
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable single-stranded DNA binding activity; single-stranded RNA binding activity; and translation initiation factor binding activity. Predicted to be involved in regulation of gene expression and transcription initiation at RNA polymerase II promoter. Predicted to be located in nucleus. Predicted to be part of RNA polymerase II, core complex. Predicted to be active in P-body. Orthologous to human POLR2G (RNA polymerase II subunit G). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See rpb-7 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    2
    Sequence:
    Chromosome: I; NC_003279.8 (3031338..3032938, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene RNA-binding protein NOB1 Neighboring gene RING-type E3 ubiquitin transferase Neighboring gene Signal peptidase complex catalytic subunit SEC11 Neighboring gene ADP-ribosylation factor-related protein 1 Neighboring gene Transporter Neighboring gene C2H2-type domain-containing protein Neighboring gene GPI ethanolamine phosphate transferase 1

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables single-stranded DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables single-stranded RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables translation initiation factor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in DNA-templated transcription initiation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in nuclear-transcribed mRNA catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in positive regulation of nuclear-transcribed mRNA poly(A) tail shortening IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in positive regulation of translational initiation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in transcription initiation at RNA polymerase II promoter IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of DNA-directed RNA polymerase complex IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in P-body IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of RNA polymerase II, core complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    DNA-directed RNA polymerase II subunit RPB7
    NP_491093.1
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      3031338..3032938 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_058692.7NP_491093.1  DNA-directed RNA polymerase II subunit RPB7 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491093.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9N3C9
      Conserved Domains (1) summary
      PTZ00162
      Location:24192
      PTZ00162; DNA-directed RNA polymerase II subunit 7; Provisional