rpl-37A Large ribosomal subunit protein eL43 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: rpl-37A
Official Full Name: Large ribosomal subunit protein eL43
Primary source: WormBase:WBGene00004456
Locus tag: CELE_Y48B6A.2
See related: AllianceGenome:WB:WBGene00004456
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable metal ion binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Orthologous to several human genes including RPL37A (ribosomal protein L37a). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See rpl-37A in Genome Data Viewer

Location:: chromosome: II

Exon count:: 1

Sequence:: Chromosome: II; NC_003280.10 (14155294..14155569)

Chromosome II - NC_003280.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Loss of rpl-43 activity results in accumulation of SQST-1 aggregates in the larval intestine.
Title: Genome-wide screen identifies signaling pathways that regulate autophagy during Caenorhabditis elegans development.

Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

Y48B6A.2 (e-PCR)
- UniSTS:321872

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables structural constituent of ribosome	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in translation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of cytosolic large ribosomal subunit	IBA Inferred from Biological aspect of Ancestor more info
part_of ribonucleoprotein complex	IEA Inferred from Electronic Annotation more info
located_in ribosome	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Large ribosomal subunit protein eL43

NP_496957.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003280.10 Reference assembly

Range

14155294..14155569

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_064556.7 → NP_496957.1 Large ribosomal subunit protein eL43 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_496957.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q9U2A8

Conserved Domains (1) summary

PTZ00255
Location:1 → 90

PTZ00255; 60S ribosomal protein L37a; Provisional