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    snb-6 V-SNARE coiled-coil homology domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 188497, updated on 9-Dec-2024

    Summary

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    Official Symbol
    snb-6
    Official Full Name
    V-SNARE coiled-coil homology domain-containing protein
    Primary source
    WormBase:WBGene00044062
    Locus tag
    CELE_T14D7.3
    See related
    AllianceGenome:WB:WBGene00044062
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable SNAP receptor activity and syntaxin binding activity. Predicted to be involved in vesicle fusion. Predicted to be located in membrane. Predicted to be part of SNARE complex. Predicted to be active in plasma membrane. Orthologous to human VAMP7 (vesicle associated membrane protein 7). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See snb-6 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    4
    Sequence:
    Chromosome: II; NC_003280.10 (8859066..8859696, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Alanine--glyoxylate aminotransferase Neighboring gene Acyltransferase 3 domain-containing protein Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein Neighboring gene UPF0046 protein T07D4.2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. MitoSNARE Assembly and Disassembly Factors Regulate Basal Autophagy and Aging in C. elegans. Gkikas I, et al. Int J Mol Sci, 2023 Feb 20. PMID 36835643, Free PMC Article
    2. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
    3. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables SNAP receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables syntaxin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in vesicle fusion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of SNARE complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    V-SNARE coiled-coil homology domain-containing protein
    NP_495887.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      8859066..8859696 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_063486.3 → NP_495887.1  V-SNARE coiled-coil homology domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_495887.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q94057
      Conserved Domains (1) summary
      pfam00957
      Location:14 → 102
      Synaptobrevin
    Nucleotide Protein
    Heading Accession and Version

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