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    F54F12.1 WSN domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 176727, updated on 9-Dec-2024

    Summary

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    Official Symbol
    F54F12.1
    Official Full Name
    WSN domain-containing protein
    Primary source
    WormBase:WBGene00010072
    Locus tag
    CELE_F54F12.1
    See related
    AllianceGenome:WB:WBGene00010072
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable protein tyrosine phosphatase activity. Predicted to be involved in protein dephosphorylation. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See F54F12.1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    10
    Sequence:
    Chromosome: III; NC_003281.10 (13049416..13055442, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene protein of unknown function WSN domain-containing protein Neighboring gene DUF1980 domain-containing protein;PGG domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Intestinal tube formation in Caenorhabditis elegans requires vang-1 and egl-15 signaling. Hoffmann M, et al. Dev Biol, 2010 Mar 15. PMID 20004187
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables protein tyrosine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    WSN domain-containing protein
    NP_499709.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      13049416..13055442 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_067308.3 → NP_499709.1  WSN domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_499709.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O17889
      Conserved Domains (2) summary
      cd00047
      Location:884 → 1127
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
      pfam00102
      Location:879 → 1127
      Y_phosphatase; Protein-tyrosine phosphatase
    Nucleotide Protein
    Heading Accession and Version

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