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    igcm-2 B-cell receptor CD22-like [ Caenorhabditis elegans ]

    Gene ID: 180913, updated on 9-Dec-2024

    Summary

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    Official Symbol
    igcm-2
    Official Full Name
    B-cell receptor CD22-like
    Primary source
    WormBase:WBGene00020130
    Locus tag
    CELE_SSSD1.1
    See related
    AllianceGenome:WB:WBGene00020130
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable cell adhesion molecule binding activity. Predicted to be involved in cell-cell adhesion. Predicted to be located in membrane. Predicted to be active in cell-cell junction and plasma membrane. Is expressed in gonad; head neurons; hypodermis; and intestine. Orthologous to several human genes including IGSF9 (immunoglobulin superfamily member 9). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See igcm-2 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    19
    Sequence:
    Chromosome: X; NC_003284.9 (6379372..6391591, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene CHCH domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene LAMP family protein lmp-1 Neighboring gene Ig-like domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Evolutionary conservation of putative suicidality-related risk genes that produce diminished motivation corrected by clozapine, lithium and antidepressants. Ajayi T, et al. Front Psychiatry, 2024. PMID 38362034, Free PMC Article
    2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables cell adhesion molecule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell-cell adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cell-cell junction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    B-cell receptor CD22-like
    NP_001362087.1
    • Confirmed by transcript evidence
    NP_001362088.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      6379372..6391591 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001375052.3 → NP_001362088.1  B-cell receptor CD22-like [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5E4M2E1
      Conserved Domains (4) summary
      smart00410
      Location:195 → 279
      IG_like; Immunoglobulin like
      cd00063
      Location:457 → 529
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam13927
      Location:290 → 352
      Ig_3; Immunoglobulin domain
      cl11960
      Location:105 → 181
      Ig; Immunoglobulin domain

    2. NM_001375051.2 → NP_001362087.1  B-cell receptor CD22-like [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5E4LXP4
      Conserved Domains (4) summary
      smart00410
      Location:214 → 298
      IG_like; Immunoglobulin like
      cd00063
      Location:476 → 548
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam13927
      Location:309 → 371
      Ig_3; Immunoglobulin domain
      cl11960
      Location:124 → 200
      Ig; Immunoglobulin domain
    Nucleotide Protein
    Heading Accession and Version

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