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    far-2 Fatty-acid and retinol-binding protein 2 [ Caenorhabditis elegans ]

    Gene ID: 176284, updated on 9-Dec-2024

    Summary

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    Official Symbol
    far-2
    Official Full Name
    Fatty-acid and retinol-binding protein 2
    Primary source
    WormBase:WBGene00001386
    Locus tag
    CELE_F02A9.3
    See related
    AllianceGenome:WB:WBGene00001386
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable fatty acid binding activity and retinol binding activity. Predicted to be located in extracellular region. Is expressed in body wall musculature; vulval muscle; and in male. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See far-2 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    2
    Sequence:
    Chromosome: III; NC_003281.10 (9081828..9082511)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Large ribosomal subunit protein mL44 Neighboring gene putative methylcrotonoyl-CoA carboxylase beta chain, mitochondrial Neighboring gene glp-1/Notch intracellular domain Neighboring gene Putative serine/threonine-protein kinase ZK507.1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The FAR proteins of parasitic nematodes: their possible involvement in the pathogenesis of infection and the use of Caenorhabditis elegans as a model system to evaluate their function. Garofalo A, et al. Med Microbiol Immunol, 2003 Feb. PMID 12592563
    2. Ligand binding properties of two Brugia malayi fatty acid and retinol (FAR) binding proteins and their vaccine efficacies against challenge infection in gerbils. Zhan B, et al. PLoS Negl Trop Dis, 2018 Oct. PMID 30296268, Free PMC Article
    3. 'Promoter trapping' in Caenorhabditis elegans. Hope IA. Development, 1991 Oct. PMID 1782857
    4. Caenorhabditis elegans reporter fusion genes generated by seamless modification of large genomic DNA clones. Dolphin CT, et al. Nucleic Acids Res, 2006 May 22. PMID 16717278, Free PMC Article
    5. The FAR protein family of the nematode Caenorhabditis elegans. Differential lipid binding properties, structural characteristics, and developmental regulation. Garofalo A, et al. J Biol Chem, 2003 Mar 7. PMID 12502713

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables fatty acid binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables lipid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables retinol binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Fatty-acid and retinol-binding protein 2
    NP_499011.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      9081828..9082511
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_066610.8 → NP_499011.1  Fatty-acid and retinol-binding protein 2 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_499011.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P34383
      Conserved Domains (1) summary
      pfam05823
      Location:33 → 174
      Gp-FAR-1; Nematode fatty acid retinoid binding protein (Gp-FAR-1)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P34383.1

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