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    wrt-2 WaRThog (hedgehog-like family) [ Caenorhabditis elegans ]

    Gene ID: 180597, updated on 9-Dec-2024

    Summary

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    Official Symbol
    wrt-2
    Official Full Name
    WaRThog (hedgehog-like family)
    Primary source
    WormBase:WBGene00006948
    Locus tag
    CELE_F52E4.6
    See related
    AllianceGenome:WB:WBGene00006948
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be active in extracellular matrix. Is expressed in hypodermis. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See wrt-2 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    8
    Sequence:
    Chromosome: X; NC_003284.9 (3092395..3094349, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Potassium channel domain-containing protein Neighboring gene ncRNA Neighboring gene Fucose-specific lectin Neighboring gene Propionyl-CoA carboxylase beta chain, mitochondrial Neighboring gene ncRNA Neighboring gene Exocyst complex component 1 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A role for the fusogen eff-1 in epidermal stem cell number robustness in Caenorhabditis elegans. Koneru SL, et al. Sci Rep, 2021 May 7. PMID 33963222, Free PMC Article
    2. The V0-ATPase mediates apical secretion of exosomes containing Hedgehog-related proteins in Caenorhabditis elegans. Liégeois S, et al. J Cell Biol, 2006 Jun 19. PMID 16785323, Free PMC Article
    3. Warthog and groundhog, novel families related to hedgehog. Bürglin TR. Curr Biol, 1996 Sep 1. PMID 8805384
    4. An Argonaute transports siRNAs from the cytoplasm to the nucleus. Guang S, et al. Science, 2008 Jul 25. PMID 18653886, Free PMC Article
    5. NHR-23 activity is necessary for C. elegans developmental progression and apical extracellular matrix structure and function. Johnson LC, et al. Development, 2023 May 15. PMID 37129010, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    is_active_in extracellular matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    WaRThog (hedgehog-like family)
    NP_508529.1
    • Product from WormBase gene class wrt;
      Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      3092395..3094349 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_076128.7 → NP_508529.1  WaRThog (hedgehog-like family) [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_508529.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q20677
    Nucleotide Protein
    Heading Accession and Version

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