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    F37A4.1 Uncharacterized protein [ Caenorhabditis elegans ]

    Gene ID: 175948, updated on 9-Dec-2024

    Summary

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    Official Symbol
    F37A4.1
    Official Full Name
    Uncharacterized protein
    Primary source
    WormBase:WBGene00018131
    Locus tag
    CELE_F37A4.1
    See related
    AllianceGenome:WB:WBGene00018131
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable monoacylglycerol lipase activity and phospholipase activity. Predicted to be involved in monoacylglycerol catabolic process and phosphatidylserine catabolic process. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 86. Orthologous to several human genes including ABHD16A (abhydrolase domain containing 16A, phospholipase). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See F37A4.1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    9
    Sequence:
    Chromosome: III; NC_003281.10 (6723389..6725724)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene BTB and MATH domain-containing protein 41 Neighboring gene Uncharacterized protein Neighboring gene tRNA-Lys Neighboring gene tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit Neighboring gene tRNA-Arg Neighboring gene Uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Germline Maintenance Through the Multifaceted Activities of GLH/Vasa in Caenorhabditis elegans P Granules. Marnik EA, et al. Genetics, 2019 Nov. PMID 31506335, Free PMC Article
    2. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables monoacylglycerol lipase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phospholipase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in monoacylglycerol catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in phosphatidylserine catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Uncharacterized protein
    NP_498475.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      6723389..6725724
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_066074.7 → NP_498475.1  Uncharacterized protein CELE_F37A4.1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_498475.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P41879
      Conserved Domains (2) summary
      pfam00561
      Location:226 → 462
      Abhydrolase_1; alpha/beta hydrolase fold
      pfam12695
      Location:247 → 341
      Abhydrolase_5; Alpha/beta hydrolase family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P41879.1

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