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    C43E11.9 60S ribosome subunit biogenesis protein NIP7 homolog [ Caenorhabditis elegans ]

    Gene ID: 172028, updated on 9-Dec-2024

    Summary

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    Official Symbol
    C43E11.9
    Official Full Name
    60S ribosome subunit biogenesis protein NIP7 homolog
    Primary source
    WormBase:WBGene00016607
    Locus tag
    CELE_C43E11.9
    See related
    AllianceGenome:WB:WBGene00016607
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable RNA binding activity. Predicted to be involved in ribosomal large subunit biogenesis. Predicted to be located in nucleus. Predicted to be part of preribosome, large subunit precursor. Predicted to be active in nucleolus. Orthologous to human NIP7 (nucleolar pre-rRNA processing protein NIP7). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See C43E11.9 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    3
    Sequence:
    Chromosome: I; NC_003279.8 (4267199..4267967, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Transcription factor TFIIIC triple barrel domain-containing protein Neighboring gene Histone-lysine N-methyltransferase Neighboring gene Crossover junction endonuclease MUS81 Neighboring gene Cell division control protein Neighboring gene SAP domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. MEX-3 interacting proteins link cell polarity to asymmetric gene expression in Caenorhabditis elegans. Huang NN, et al. Development, 2002 Feb. PMID 11830574
    2. Functional identification of microRNA-centered complexes in C. elegans. Hebbar S, et al. Sci Rep, 2022 May 3. PMID 35504914, Free PMC Article
    3. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
    4. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    5. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in ribosomal large subunit biogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in ribosome assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in ribosome biogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of preribosome, large subunit precursor IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    60S ribosome subunit biogenesis protein NIP7 homolog
    NP_491342.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      4267199..4267967 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_058941.6 → NP_491342.1  60S ribosome subunit biogenesis protein NIP7 homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491342.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      P91154
      Conserved Domains (1) summary
      COG1374
      Location:1 → 176
      NIP7; Rbosome biogenesis protein Nip4, contains PUA domain [Translation, ribosomal structure and biogenesis]
    Nucleotide Protein
    Heading Accession and Version

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