C56C10.9 45 kDa calcium-binding protein [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: C56C10.9
Official Full Name: 45 kDa calcium-binding protein
Primary source: WormBase:WBGene00016965
Locus tag: CELE_C56C10.9
See related: AllianceGenome:WB:WBGene00016965
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable calcium ion binding activity. Predicted to be involved in calcium-ion regulated exocytosis. Predicted to be located in Golgi lumen. Predicted to be active in endoplasmic reticulum. Orthologous to human SDF4 (stromal cell derived factor 4). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See C56C10.9 in Genome Data Viewer

Location:: chromosome: II

Exon count:: 6

Sequence:: Chromosome: II; NC_003280.10 (6591048..6592351, complement)

Chromosome II - NC_003280.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

C56C10.10 (e-PCR)
- UniSTS:313958

C56C10.9 (e-PCR)
- UniSTS:309439

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables calcium ion binding	IBA Inferred from Biological aspect of Ancestor more info
enables calcium ion binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in calcium-ion regulated exocytosis	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in Golgi apparatus	IEA Inferred from Electronic Annotation more info
located_in Golgi lumen	IEA Inferred from Electronic Annotation more info
is_active_in endoplasmic reticulum	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: 45 kDa calcium-binding protein

NP_495338.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003280.10 Reference assembly

Range

6591048..6592351 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_062937.8 → NP_495338.1 45 kDa calcium-binding protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_495338.1

Status: REVIEWED

UniProtKB/TrEMBL

Q18887

Conserved Domains (3) summary

COG5126
Location:194 → 289

FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]

pfam13499
Location:67 → 127

EF-hand_7; EF-hand domain pair

cl08302
Location:67 → 126

EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...