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    prmn-1 PRoMiNin (5-transmembrane domain glycoprotein) homolog [ Caenorhabditis elegans ]

    Gene ID: 181330, updated on 9-Dec-2024

    Summary

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    Official Symbol
    prmn-1
    Official Full Name
    PRoMiNin (5-transmembrane domain glycoprotein) homolog
    Primary source
    WormBase:WBGene00008571
    Locus tag
    CELE_F08B12.1
    See related
    AllianceGenome:WB:WBGene00008571
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be located in membrane. Human ortholog(s) of this gene implicated in cone-rod dystrophy 12; retinal macular dystrophy 2; and retinitis pigmentosa 41. Orthologous to human PROM1 (prominin 1) and PROM2 (prominin 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See prmn-1 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    20
    Sequence:
    Chromosome: X; NC_003284.9 (11385084..11392776)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Peroxisome assembly protein 12 Neighboring gene Ion_trans_2 domain-containing protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional genomics of the cilium, a sensory organelle. Blacque OE, et al. Curr Biol, 2005 May 24. PMID 15916950
    2. The relationship between intraflagellar transport and upstream protein trafficking pathways and macrocyclic lactone resistance in Caenorhabditis elegans. Brinzer RA, et al. G3 (Bethesda), 2024 Mar 6. PMID 38227795, Free PMC Article
    3. Amino acid and protein specificity of protein fatty acylation in C. elegans. Zhang B, et al. Proc Natl Acad Sci U S A, 2024 Jan 30. PMID 38252833, Free PMC Article
    4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    PRoMiNin (5-transmembrane domain glycoprotein) homolog
    NP_509907.1
    • Product from WormBase gene class prmn;
      Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      11385084..11392776
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_077506.6 → NP_509907.1  PRoMiNin (5-transmembrane domain glycoprotein) homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_509907.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q19188
      Conserved Domains (2) summary
      pfam05478
      Location:13 → 816
      Prominin; Prominin
      cl23720
      Location:686 → 763
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)
    Nucleotide Protein
    Heading Accession and Version

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