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    F52E1.9 Phosphatidylinositol-4,5-bisphosphate 4-phosphatase [ Caenorhabditis elegans ]

    Gene ID: 186115, updated on 9-Dec-2024

    Summary

    Official Symbol
    F52E1.9
    Official Full Name
    Phosphatidylinositol-4,5-bisphosphate 4-phosphatase
    Primary source
    WormBase:WBGene00018697
    Locus tag
    CELE_F52E1.9
    See related
    AllianceGenome:WB:WBGene00018697
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity. Predicted to be involved in phosphatidylinositol dephosphorylation. Predicted to be located in endosome; lysosome; and membrane. Predicted to be active in bounding membrane of organelle and plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See F52E1.9 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    5
    Sequence:
    Chromosome: V; NC_003283.11 (8398142..8402636, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Guanylate cyclase;Receptor-type guanylate cyclase gcy-7 Neighboring gene Lysosomal acid phosphatase Neighboring gene TPX2 domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene C-type lectin domain-containing protein Neighboring gene putative V-type proton ATPase subunit H 1

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in phosphatidylinositol dephosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in phosphatidylinositol dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in endosome IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in late endosome membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in late endosome membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in lysosomal membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in lysosomal membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in lysosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in phagocytic vesicle membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    Phosphatidylinositol-4,5-bisphosphate 4-phosphatase
    NP_001368695.1
    • Confirmed by transcript evidence
    NP_001379938.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      8398142..8402636 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001392560.1NP_001379938.1  Phosphatidylinositol-4,5-bisphosphate 4-phosphatase [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q20664
    2. NM_001380705.1NP_001368695.1  Phosphatidylinositol-4,5-bisphosphate 4-phosphatase [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A2K5ATY3