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    C47B2.2 Uracil phosphoribosyltransferase homolog [ Caenorhabditis elegans ]

    Gene ID: 3565732, updated on 9-Dec-2024

    Summary

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    Official Symbol
    C47B2.2
    Official Full Name
    Uracil phosphoribosyltransferase homolog
    Primary source
    WormBase:WBGene00008131
    Locus tag
    CELE_C47B2.2
    See related
    AllianceGenome:WB:WBGene00008131
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable glycosyltransferase activity. Located in striated muscle dense body. Orthologous to human UPRT (uracil phosphoribosyltransferase homolog). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See C47B2.2 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    4
    Sequence:
    Chromosome: I; NC_003279.8 (12962042..12964579, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene DUF38 domain-containing protein Neighboring gene F-box domain-containing protein Neighboring gene Tubulin alpha-2 chain Neighboring gene Proteasome subunit beta

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Determining the sub-cellular localization of proteins within Caenorhabditis elegans body wall muscle. Meissner B, et al. PLoS One, 2011. PMID 21611156, Free PMC Article
    2. SIN-3 acts in distinct complexes to regulate the germline transcriptional program in Caenorhabditis elegans. Robert VJ, et al. Development, 2023 Nov 1. PMID 37818613, Free PMC Article
    3. Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans. Artan M, et al. J Biol Chem, 2022 Sep. PMID 35933017, Free PMC Article
    4. Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling. Artan M, et al. J Biol Chem, 2021 Sep. PMID 34416233, Free PMC Article
    5. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in striated muscle dense body HDA PubMed 

    General protein information

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    Preferred Names
    Uracil phosphoribosyltransferase homolog
    NP_001252032.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      12962042..12964579 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001265103.4 → NP_001252032.1  Uracil phosphoribosyltransferase homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001252032.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9U3L5
      Conserved Domains (1) summary
      pfam14681
      Location:43 → 215
      UPRTase; Uracil phosphoribosyltransferase
    Nucleotide Protein
    Heading Accession and Version

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