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    angl-1 Endonuclease/exonuclease/phosphatase domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 189127, updated on 9-Dec-2024

    Summary

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    Official Symbol
    angl-1
    Official Full Name
    Endonuclease/exonuclease/phosphatase domain-containing protein
    Primary source
    WormBase:WBGene00020955
    Locus tag
    CELE_W02G9.5
    See related
    AllianceGenome:WB:WBGene00020955
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable mRNA 3'-UTR binding activity. Is expressed in several structures, including ganglia; intestine; pharyngeal muscle cell; postcloacal sensillum; and ventral cord neurons. Orthologous to human ANGEL1 (angel homolog 1) and ANGEL2 (angel homolog 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See angl-1 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    8
    Sequence:
    Chromosome: V; NC_003283.11 (2653083..2662655)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene SOCS box domain-containing protein Neighboring gene ncRNA Neighboring gene Triokinase/FMN cyclase Neighboring gene ncRNA Neighboring gene Putative nudix hydrolase 2 Neighboring gene tRNA-Thr Neighboring gene ncRNA Neighboring gene CUB domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Ccr4-Not deadenylase complex constitutes the main poly(A) removal activity in C. elegans. Nousch M, et al. J Cell Sci, 2013 Sep 15. PMID 23843623
    2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables endonuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mRNA 3'-UTR binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Endonuclease/exonuclease/phosphatase domain-containing protein
    NP_001303707.1
    • Partially confirmed by transcript evidence
    NP_001303752.1
    • Confirmed by transcript evidence
    NP_001364845.1
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      2653083..2662655
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001316778.3 → NP_001303707.1  Endonuclease/exonuclease/phosphatase domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0M9JJ86
      Conserved Domains (1) summary
      cl00490
      Location:280 → 478
      EEP; Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily

    2. NM_001377589.2 → NP_001364845.1  Endonuclease/exonuclease/phosphatase domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0M7RFG6
      Conserved Domains (1) summary
      cl00490
      Location:214 → 412
      EEP; Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily

    3. NM_001316823.4 → NP_001303752.1  Endonuclease/exonuclease/phosphatase domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0M7RDV8
      Conserved Domains (1) summary
      cl00490
      Location:75 → 273
      EEP; Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily
    Nucleotide Protein
    Heading Accession and Version

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