C34F6.10 Fibronectin type-III domain-containing protein [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: C34F6.10
Official Full Name: Fibronectin type-III domain-containing protein
Primary source: WormBase:WBGene00007944
Locus tag: CELE_C34F6.10
See related: AllianceGenome:WB:WBGene00007944
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to be involved in axon guidance; cell-cell adhesion; and neuron migration. Predicted to be located in membrane. Predicted to be active in axonal growth cone; cell surface; and plasma membrane. Is expressed in RIH; anal sphincter muscle; body wall musculature; and rectum. Orthologous to human FNDC3A (fibronectin type III domain containing 3A) and FNDC3B (fibronectin type III domain containing 3B). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See C34F6.10 in Genome Data Viewer

Location:: chromosome: X

Exon count:: 16

Sequence:: Chromosome: X; NC_003284.9 (11229212..11240635, complement)

Chromosome X - NC_003284.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

C34F6.10 (e-PCR)
- UniSTS:309251

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Process	Evidence Code	Pubs
involved_in axon guidance	IBA Inferred from Biological aspect of Ancestor more info
involved_in cell-cell adhesion	IBA Inferred from Biological aspect of Ancestor more info
involved_in neuron migration	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in axonal growth cone	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: Fibronectin type-III domain-containing protein

NP_001360582.1

Confirmed by transcript evidence

NP_001360583.1

Confirmed by transcript evidence

NP_001370013.1

Confirmed by transcript evidence

NP_001371006.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003284.9 Reference assembly

Range

11229212..11240635 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001383644.1 → NP_001371006.1 Fibronectin type-III domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

A0A486WY49

Conserved Domains (1) summary

cd00063
Location:1076 → 1167

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
NM_001373501.3 → NP_001360582.1 Fibronectin type-III domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

A0A486WVV5

Conserved Domains (1) summary

cd00063
Location:1106 → 1197

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
NM_001383645.1 → NP_001370013.1 Fibronectin type-III domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

G5EF49

Conserved Domains (1) summary

cd00063
Location:1100 → 1191

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
NM_001373500.3 → NP_001360583.1 Fibronectin type-III domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

A0A486WX36

Conserved Domains (1) summary

cd00063
Location:1082 → 1173

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...