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    ndub-5 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial [ Caenorhabditis elegans ]

    Gene ID: 173963, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ndub-5
    Official Full Name
    NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial
    Primary source
    WormBase:WBGene00016118
    Locus tag
    CELE_C25H3.9
    See related
    AllianceGenome:WB:WBGene00016118
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be located in membrane. Predicted to be part of respiratory chain complex I. Is expressed in hypodermis; intestine; and pharynx. Orthologous to human NDUFB5 (NADH:ubiquinone oxidoreductase subunit B5). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ndub-5 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    5
    Sequence:
    Chromosome: II; NC_003280.10 (5690137..5691353, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Ricin B-type lectin domain-containing protein Neighboring gene EASAFGDIIGELKGKGLGGRMRF-amide Neighboring gene pseudo Neighboring gene SUI1 domain-containing protein Neighboring gene Thioesterase domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mitochondrial modulation of phosphine toxicity and resistance in Caenorhabditis elegans. Zuryn S, et al. Toxicol Sci, 2008 Mar. PMID 17998274
    2. The role of mitochondria in the life of the nematode, Caenorhabditis elegans. Tsang WY, et al. Biochim Biophys Acta, 2003 Jul 14. PMID 12853115
    3. Gene regulatory network inference in long-lived C. elegans reveals modular properties that are predictive of novel aging genes. Suriyalaksh M, et al. iScience, 2022 Jan 21. PMID 35036864, Free PMC Article
    4. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of respiratory chain complex I IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of respiratory chain complex I ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial
    NP_741000.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      5690137..5691353 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_171001.8 → NP_741000.2  NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_741000.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2KYV1
      Conserved Domains (1) summary
      pfam09781
      Location:1 → 167
      NDUF_B5; NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit
    Nucleotide Protein
    Heading Accession and Version

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