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    rig-5 Ig-like domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 172791, updated on 9-Dec-2024

    Summary

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    Official Symbol
    rig-5
    Official Full Name
    Ig-like domain-containing protein
    Primary source
    WormBase:WBGene00004372
    Locus tag
    CELE_C36F7.4
    See related
    AllianceGenome:WB:WBGene00004372
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be active in neuron projection. Is expressed in g1; intestine; and neurons. Human ortholog(s) of this gene implicated in ovarian cancer. Orthologous to several human genes including IGLON5 (IgLON family member 5); LSAMP (limbic system associated membrane protein); and NEGR1 (neuronal growth regulator 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See rig-5 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    13
    Sequence:
    Chromosome: I; NC_003279.8 (9565389..9574377, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene tRNA-Ile Neighboring gene tRNA-Ile Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene Collagen triple helix repeat protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. wrk-1 and rig-5 control pioneer and follower axon navigation in the ventral nerve cord of Caenorhabditis elegans in a nid-1 mutant background. Feresten AH, et al. Genetics, 2023 Mar 2. PMID 36573271, Free PMC Article
    2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. wrk-1 and rig-5 control pioneer and follower axon navigation in the ventral nerve cord of Caenorhabditis elegans in a nid-1 mutant background.
      Title: wrk-1 and rig-5 control pioneer and follower axon navigation in the ventral nerve cord of Caenorhabditis elegans in a nid-1 mutant background.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    is_active_in neuron projection IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Ig-like domain-containing protein
    NP_001122427.1
    • Partially confirmed by transcript evidence
    NP_001122428.1
    • Confirmed by transcript evidence
    NP_001251129.1
    • Partially confirmed by transcript evidence
    NP_001251131.1
    • Partially confirmed by transcript evidence
    NP_001251132.1
    • Confirmed by transcript evidence
    NP_001366862.1
    • Confirmed by transcript evidence
    NP_492535.1
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      9565389..9574377 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001264200.4 → NP_001251129.1  Ig-like domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001251129.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2FLI8
      Conserved Domains (3) summary
      smart00409
      Location:294 → 380
      IG; Immunoglobulin
      smart00410
      Location:92 → 189
      IG_like; Immunoglobulin like
      pfam13927
      Location:191 → 270
      Ig_3; Immunoglobulin domain

    2. NM_001381092.1 → NP_001366862.1  Ig-like domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q93350
      Conserved Domains (4) summary
      smart00410
      Location:2 → 93
      IG_like; Immunoglobulin like
      pfam13927
      Location:143 → 225
      Ig_3; Immunoglobulin domain
      cd00096
      Location:146 → 152
      Ig; Ig strand A' [structural motif]
      cl11960
      Location:87 → 140
      Ig; Immunoglobulin domain

    3. NM_060134.4 → NP_492535.1  Ig-like domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_492535.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9NAR0
      Conserved Domains (2) summary
      smart00409
      Location:92 → 183
      IG; Immunoglobulin
      smart00410
      Location:240 → 326
      IG_like; Immunoglobulin like

    4. NM_001264203.2 → NP_001251132.1  Ig-like domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001251132.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2FLI7
      Conserved Domains (2) summary
      smart00409
      Location:243 → 329
      IG; Immunoglobulin
      smart00410
      Location:147 → 233
      IG_like; Immunoglobulin like

    5. NM_001128955.4 → NP_001122427.1  Ig-like domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001122427.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A7UQ11
      Conserved Domains (3) summary
      smart00409
      Location:294 → 380
      IG; Immunoglobulin
      smart00410
      Location:92 → 189
      IG_like; Immunoglobulin like
      pfam13927
      Location:191 → 270
      Ig_3; Immunoglobulin domain

    6. NM_001264202.1 → NP_001251131.1  Ig-like domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001251131.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      C6KRM7
      Conserved Domains (3) summary
      smart00409
      Location:294 → 380
      IG; Immunoglobulin
      smart00410
      Location:92 → 189
      IG_like; Immunoglobulin like
      pfam13927
      Location:191 → 270
      Ig_3; Immunoglobulin domain

    7. NM_001128956.4 → NP_001122428.1  Ig-like domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001122428.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B2D6P2
      Conserved Domains (1) summary
      smart00410
      Location:34 → 120
      IG_like; Immunoglobulin like
    Nucleotide Protein
    Heading Accession and Version

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