aman-3 Alpha-mannosidase [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: aman-3
Official Full Name: Alpha-mannosidase
Primary source: WormBase:WBGene00018594
Locus tag: CELE_F48C1.1
See related: AllianceGenome:WB:WBGene00018594
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable alpha-mannosidase activity. Predicted to be involved in N-glycan processing. Predicted to be located in membrane. Predicted to be active in Golgi membrane. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See aman-3 in Genome Data Viewer

Location:: chromosome: I

Exon count:: 19

Sequence:: Chromosome: I; NC_003279.8 (5325549..5330230)

Chromosome I - NC_003279.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

F48C1.1 (e-PCR)
- UniSTS:311664

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables alpha-mannosidase activity	IBA Inferred from Biological aspect of Ancestor more info
enables alpha-mannosidase activity	IEA Inferred from Electronic Annotation more info
enables carbohydrate binding	IEA Inferred from Electronic Annotation more info
enables catalytic activity	IEA Inferred from Electronic Annotation more info
enables hydrolase activity, acting on glycosyl bonds	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in N-glycan processing	IBA Inferred from Biological aspect of Ancestor more info
involved_in carbohydrate metabolic process	IEA Inferred from Electronic Annotation more info
involved_in mannose metabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in Golgi membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Alpha-mannosidase

NP_001361919.1

Confirmed by transcript evidence

NP_001362173.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003279.8 Reference assembly

Range

5325549..5330230

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001374890.2 → NP_001362173.1 Alpha-mannosidase [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

A0A5K1I7Y9

Conserved Domains (2) summary

PLN02701
Location:117 → 977

PLN02701; alpha-mannosidase

cd10809
Location:118 → 452

GH38N_AMII_GMII_SfManIII_like; N-terminal catalytic domain of Golgi alpha-mannosidase II, Spodoptera frugiperda Sf9 alpha-mannosidase III, and similar proteins; glycoside hydrolase family 38 (GH38)
NM_001374889.1 → NP_001361919.1 Alpha-mannosidase [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

O01574

Conserved Domains (2) summary

PLN02701
Location:117 → 978

PLN02701; alpha-mannosidase

cd10809
Location:118 → 452

GH38N_AMII_GMII_SfManIII_like; N-terminal catalytic domain of Golgi alpha-mannosidase II, Spodoptera frugiperda Sf9 alpha-mannosidase III, and similar proteins; glycoside hydrolase family 38 (GH38)