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    E04F6.4 PLD phosphodiesterase domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 174179, updated on 9-Dec-2024

    Summary

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    Official Symbol
    E04F6.4
    Official Full Name
    PLD phosphodiesterase domain-containing protein
    Primary source
    WormBase:WBGene00017124
    Locus tag
    CELE_E04F6.4
    See related
    AllianceGenome:WB:WBGene00017124
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable catalytic activity. Predicted to be involved in lipid catabolic process. Predicted to be located in membrane. Orthologous to human PLD5 (phospholipase D family member 5). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See E04F6.4 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    10
    Sequence:
    Chromosome: II; NC_003280.10 (7189420..7192508)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Phosphodiesterase delta-like protein Neighboring gene G_PROTEIN_RECEP_F1_2 domain-containing protein Neighboring gene Very long-chain specific acyl-CoA dehydrogenase, mitochondrial Neighboring gene ncRNA Neighboring gene MaoC-like domain-containing protein Neighboring gene Secreted protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Large-scale RNAi screens identify novel genes that interact with the C. elegans retinoblastoma pathway as well as splicing-related components with synMuv B activity. Ceron J, et al. BMC Dev Biol, 2007 Apr 6. PMID 17417969, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in lipid catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    PLD phosphodiesterase domain-containing protein
    NP_495492.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      7189420..7192508
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_063091.7 → NP_495492.1  PLD phosphodiesterase domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_495492.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q19056
      Conserved Domains (4) summary
      PHA03255
      Location:49 → 182
      PHA03255; BDLF3; Provisional
      PHA03003
      Location:181 → 576
      PHA03003; palmytilated EEV membrane glycoprotein; Provisional
      cd09106
      Location:195 → 352
      PLDc_vPLD3_4_5_like_1; Putative catalytic domain, repeat 1, of vertebrate phospholipases, PLD3, PLD4 and PLD5, viral envelope proteins K4 and p37, and similar proteins
      cd09107
      Location:393 → 569
      PLDc_vPLD3_4_5_like_2; Putative catalytic domain, repeat 2, of vertebrate phospholipases, PLD3, PLD4 and PLD5, viral envelope proteins K4 and p37, and similar proteins
    Nucleotide Protein
    Heading Accession and Version

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