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    ZK354.8 Protein-tyrosine phosphatase [ Caenorhabditis elegans ]

    Gene ID: 191295, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ZK354.8
    Official Full Name
    Protein-tyrosine phosphatase
    Primary source
    WormBase:WBGene00022709
    Locus tag
    CELE_ZK354.8
    See related
    AllianceGenome:WB:WBGene00022709
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable protein tyrosine phosphatase activity. Predicted to be involved in protein dephosphorylation. Orthologous to human PTPN9 (protein tyrosine phosphatase non-receptor type 9). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ZK354.8 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    8
    Sequence:
    Chromosome: IV; NC_003282.8 (5303988..5306140, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Major sperm protein Neighboring gene pseudo Neighboring gene Serine/threonine-protein phosphatase Neighboring gene MSP domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables protein tyrosine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Protein-tyrosine phosphatase
    NP_500775.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      5303988..5306140 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_068374.5 → NP_500775.1  Protein-tyrosine phosphatase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_500775.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      P91568
      Conserved Domains (2) summary
      smart00194
      Location:200 → 451
      PTPc; Protein tyrosine phosphatase, catalytic domain
      cd00047
      Location:225 → 451
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    Nucleotide Protein
    Heading Accession and Version

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