algn-9 Alpha-1,2-mannosyltransferase algn-9 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: algn-9
Official Full Name: Alpha-1,2-mannosyltransferase algn-9
Primary source: WormBase:WBGene00007556
Locus tag: CELE_C14A4.3
See related: AllianceGenome:WB:WBGene00007556
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable alpha-1,2-mannosyltransferase activity. Predicted to be involved in protein N-linked glycosylation. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Il. Orthologous to human ALG9 (ALG9 alpha-1,2-mannosyltransferase). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See algn-9 in Genome Data Viewer

Location:: chromosome: II

Exon count:: 6

Sequence:: Chromosome: II; NC_003280.10 (10584336..10587925)

Chromosome II - NC_003280.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

C14A4.2 (e-PCR)
- UniSTS:321217

C14A4.3 (e-PCR)
- UniSTS:321218

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables alpha-1,2-mannosyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables glycosyltransferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in protein N-linked glycosylation	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein glycosylation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info
is_active_in endoplasmic reticulum membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in endoplasmic reticulum membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Alpha-1,2-mannosyltransferase algn-9

NP_496282.2

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003280.10 Reference assembly

Range

10584336..10587925

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_063881.7 → NP_496282.2 Alpha-1,2-mannosyltransferase algn-9 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_496282.2

Status: REVIEWED

UniProtKB/Swiss-Prot

P54002

Conserved Domains (1) summary

pfam03901
Location:55 → 472

Glyco_transf_22; Alg9-like mannosyltransferase family