yju-2 Splicing factor YJU2 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: yju-2
Official Full Name: Splicing factor YJU2
Primary source: WormBase:WBGene00018149
Locus tag: CELE_F37C12.1
See related: AllianceGenome:WB:WBGene00018149
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable metal ion binding activity. Predicted to be involved in RNA splicing. Predicted to be located in nucleus. Predicted to be part of U2-type catalytic step 1 spliceosome. Is expressed in several structures, including anal depressor muscle; nervous system; pharynx; reproductive system; and tail. Orthologous to human YJU2 (YJU2 splicing factor homolog). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See yju-2 in Genome Data Viewer

Location:: chromosome: III

Exon count:: 7

Sequence:: Chromosome: III; NC_003281.10 (7184336..7187868)

Chromosome III - NC_003281.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

F37C12.1 (e-PCR)
- UniSTS:320064

F37C12.14 (e-PCR)
- UniSTS:316759

F37C12.2 (e-PCR)
- UniSTS:310179

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in RNA splicing	IBA Inferred from Biological aspect of Ancestor more info
involved_in RNA splicing	IEA Inferred from Electronic Annotation more info
involved_in generation of catalytic spliceosome for first transesterification step	IEA Inferred from Electronic Annotation more info
involved_in mRNA processing	IEA Inferred from Electronic Annotation more info
involved_in mRNA splicing, via spliceosome	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of U2-type catalytic step 1 spliceosome	IBA Inferred from Biological aspect of Ancestor more info
part_of U2-type catalytic step 1 spliceosome	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
part_of spliceosomal complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Splicing factor YJU2

NP_498576.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003281.10 Reference assembly

Range

7184336..7187868

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_066175.7 → NP_498576.1 Splicing factor YJU2 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_498576.1

Status: REVIEWED

UniProtKB/TrEMBL

Q20124

Conserved Domains (2) summary

COG5134
Location:11 → 148

COG5134; Uncharacterized conserved protein [Function unknown]

pfam04502
Location:10 → 220

DUF572; Family of unknown function (DUF572)