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    ZK228.4 N-acetyltransferase domain-containing protein;YitH/HolE acetyltransferase (GNAT) domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 180201, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ZK228.4
    Official Full Name
    N-acetyltransferase domain-containing protein;YitH/HolE acetyltransferase (GNAT) domain-containing protein
    Primary source
    WormBase:WBGene00013947
    Locus tag
    CELE_ZK228.4
    See related
    AllianceGenome:WB:WBGene00013947
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Involved in innate immune response. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ZK228.4 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    6
    Sequence:
    Chromosome: V; NC_003283.11 (18462787..18465426)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene YitH/HolE acetyltransferase (GNAT) domain-containing protein Neighboring gene tRNA Neighboring gene pseudo Neighboring gene Ovule protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A conserved role for a GATA transcription factor in regulating epithelial innate immune responses. Shapira M, et al. Proc Natl Acad Sci U S A, 2006 Sep 19. PMID 16968778, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables acyltransferase activity, transferring groups other than amino-acyl groups IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in innate immune response HEP PubMed 

    General protein information

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    Preferred Names
    N-acetyltransferase domain-containing protein;YitH/HolE acetyltransferase (GNAT) domain-containing protein
    NP_001123078.1
    • Confirmed by transcript evidence
    NP_001263925.1
    • Confirmed by transcript evidence
    NP_507615.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      18462787..18465426
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001129606.2 → NP_001123078.1  N-acetyltransferase domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001123078.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A5Z2W6
      Conserved Domains (3) summary
      pfam00583
      Location:12 → 103
      Acetyltransf_1; Acetyltransferase (GNAT) family
      pfam06852
      Location:71 → 175
      DUF1248; Protein of unknown function (DUF1248)
      pfam18014
      Location:168 → 238
      Acetyltransf_18; Acetyltransferase (GNAT) domain

    2. NM_001276996.2 → NP_001263925.1  YitH/HolE acetyltransferase (GNAT) domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001263925.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      K8FDY8
      Conserved Domains (3) summary
      cd04301
      Location:13 → 64
      NAT_SF; N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate
      pfam06852
      Location:32 → 136
      DUF1248; Protein of unknown function (DUF1248)
      pfam18014
      Location:129 → 199
      Acetyltransf_18; Acetyltransferase (GNAT) domain

    3. NM_075214.4 → NP_507615.1  N-acetyltransferase domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_507615.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O46010
      Conserved Domains (1) summary
      pfam06852
      Location:2 → 160
      DUF1248; Protein of unknown function (DUF1248)
    Nucleotide Protein
    Heading Accession and Version

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