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    • Showing Current items.

    tbc-1 TBC1 domain family member 23 [ Caenorhabditis elegans ]

    Gene ID: 181592, updated on 9-Dec-2024

    Summary

    Official Symbol
    tbc-1
    Official Full Name
    TBC1 domain family member 23
    Primary source
    WormBase:WBGene00008974
    Locus tag
    CELE_F20D1.2
    See related
    AllianceGenome:WB:WBGene00008974
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in retrograde transport, endosome to Golgi and vesicle tethering to Golgi. Predicted to be located in Golgi apparatus and cytosol. Predicted to be active in trans-Golgi network. Is expressed in anterior gonad arm. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 11. Orthologous to human TBC1D23 (TBC1 domain family member 23). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See tbc-1 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    13
    Sequence:
    Chromosome: X; NC_003284.9 (14970751..14974779)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Calcium channel flower Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Protein Skeletor Neighboring gene ncRNA Neighboring gene Essential MCU regulator, mitochondrial

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in retrograde transport, endosome to Golgi IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in retrograde transport, endosome to Golgi IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in vesicle tethering to Golgi IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in trans-Golgi network IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    TBC1 domain family member 23
    NP_510485.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      14970751..14974779
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_078084.8NP_510485.2  TBC1 domain family member 23 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_510485.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q93534
      Conserved Domains (2) summary
      smart00450
      Location:321421
      RHOD; Rhodanese Homology Domain
      cl02495
      Location:83230
      RabGAP-TBC; Rab-GTPase-TBC domain