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    tspo-1 TspO/MBR family protein [ Caenorhabditis elegans ]

    Gene ID: 7040157, updated on 9-Dec-2024

    Summary

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    Official Symbol
    tspo-1
    Official Full Name
    TspO/MBR family protein
    Primary source
    WormBase:WBGene00077771
    Locus tag
    CELE_C41G7.9
    See related
    AllianceGenome:WB:WBGene00077771
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be located in membrane. Predicted to be active in mitochondrial outer membrane. Orthologous to several human genes including TSPO (translocator protein). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See tspo-1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    5
    Sequence:
    Chromosome: I; NC_003279.8 (9514998..9516776, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene miscRNA Neighboring gene Kinesin motor domain-containing protein Neighboring gene Messenger RNA-binding inhibitor of apoptosis 1 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. BPA interferes with StAR-mediated mitochondrial cholesterol transport to induce germline dysfunctions. Chen Y, et al. Reprod Toxicol, 2019 Dec. PMID 31445225, Free PMC Article
    2. A modified TurboID approach identifies tissue-specific centriolar components in C. elegans. Holzer E, et al. PLoS Genet, 2022 Apr. PMID 35442950, Free PMC Article
    3. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in mitochondrial outer membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    TspO/MBR family protein
    NP_001251116.1
    • Confirmed by transcript evidence
    NP_001251117.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      9514998..9516776 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001264188.4 → NP_001251117.1  TspO/MBR family protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001251117.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B3WFW9
      Conserved Domains (1) summary
      pfam03073
      Location:38 → 161
      TspO_MBR; TspO/MBR family

    2. NM_001264187.4 → NP_001251116.1  TspO/MBR family protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001251116.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      C7FZU5
      Conserved Domains (1) summary
      pfam03073
      Location:79 → 202
      TspO_MBR; TspO/MBR family
    Nucleotide Protein
    Heading Accession and Version

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