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    oat-1 Major facilitator superfamily (MFS) profile domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 177649, updated on 9-Dec-2024

    Summary

    Official Symbol
    oat-1
    Official Full Name
    Major facilitator superfamily (MFS) profile domain-containing protein
    Primary source
    WormBase:WBGene00003837
    Locus tag
    CELE_T01B11.7
    See related
    AllianceGenome:WB:WBGene00003837
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in Lynch syndrome and mismatch repair cancer syndrome. Orthologous to several human genes including SLC22A10 (solute carrier family 22 member 10); SLC22A12 (solute carrier family 22 member 12); and SLC22A17 (solute carrier family 22 member 17). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See oat-1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    10
    Sequence:
    Chromosome: IV; NC_003282.8 (8464752..8472593, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ADP/ATP translocase Neighboring gene MFS domain-containing protein;Major facilitator superfamily (MFS) profile domain-containing protein Neighboring gene Transmembrane protein Neighboring gene Saposin B-type domain-containing protein Neighboring gene Helix-loop-helix protein hlh-12

    General gene information

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    located_in membrane  

    General protein information

    Preferred Names
    Major facilitator superfamily (MFS) profile domain-containing protein
    NP_501442.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      8464752..8472593 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_069041.6NP_501442.2  Major facilitator superfamily (MFS) profile domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_501442.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EDU0
      Conserved Domains (1) summary
      TIGR00898
      Location:36513
      2A0119; cation transport protein
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