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    Nrm nurim [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361791, updated on 27-Nov-2024

    Summary

    Official Symbol
    Nrmprovided by RGD
    Official Full Name
    nurimprovided by RGD
    Primary source
    RGD:1302966
    See related
    EnsemblRapid:ENSRNOG00000071251 AllianceGenome:RGD:1302966
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be located in nuclear envelope. Predicted to be active in nuclear membrane. Human ortholog(s) of this gene implicated in alcohol dependence. Orthologous to human NRM (nurim). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Lung (RPKM 39.8), Spleen (RPKM 28.6) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Nrm in Genome Data Viewer
    Location:
    20p12
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 20 NC_086038.1 (2893126..2897725, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 20 NC_051355.1 (2888321..2892804, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (3397834..3402264, complement)

    Chromosome 20 - NC_086038.1Genomic Context describing neighboring genes Neighboring gene DEAH-box helicase 16 Neighboring gene protein phosphatase 1, regulatory subunit 18 Neighboring gene microRNA 6328 Neighboring gene mediator of DNA damage checkpoint 1 Neighboring gene tubulin, beta 5 class I

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in nuclear envelope ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear envelope ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in nuclear inner membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in nuclear membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nuclear membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    nurim
    Names
    nuclear envelope membrane protein
    nuclear rim protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_212508.2NP_997673.1  nurim

      See identical proteins and their annotated locations for NP_997673.1

      Status: VALIDATED

      Source sequence(s)
      AW435457, BP490795, BP504258, DV724730
      UniProtKB/Swiss-Prot
      Q6MG14
      Related
      ENSRNOP00000001085.3, ENSRNOT00000001085.7

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086038.1 Reference GRCr8

      Range
      2893126..2897725 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039098800.2XP_038954728.1  nurim isoform X1

      UniProtKB/TrEMBL
      A0A0G2JZF3