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    Cage1 cancer antigen 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 306872, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Cage1provided by RGD
    Official Full Name
    cancer antigen 1provided by RGD
    Primary source
    RGD:1306102
    See related
    EnsemblRapid:ENSRNOG00000024111 AllianceGenome:RGD:1306102
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Ctag3
    Summary
    Orthologous to human CAGE1 (cancer antigen 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward (RPKM 1101.8) See more
    Orthologs
    human mouse all
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    Genomic context

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    See Cage1 in Genome Data Viewer
    Location:
    17p12
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (26995671..27033740)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (26789975..26828210)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (27452506..27490853)

    Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102546383 Neighboring gene RIO kinase 1 Neighboring gene uncharacterized LOC120097850 Neighboring gene signal sequence receptor subunit 1 Neighboring gene uncharacterized LOC134482845 Neighboring gene ras responsive element binding protein 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    General protein information

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    Preferred Names
    cancer-associated gene 1 protein homolog
    Names
    CAGE-1
    CT3 homolog
    cancer/testis antigen 3 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001012052.1 → NP_001012052.1  cancer-associated gene 1 protein homolog

      See identical proteins and their annotated locations for NP_001012052.1

      Status: PROVISIONAL

      Source sequence(s)
      BC081934
      UniProtKB/Swiss-Prot
      Q66HB6
      UniProtKB/TrEMBL
      A6J7B4
      Related
      ENSRNOP00000101637.1, ENSRNOT00000123244.1
      Conserved Domains (3) summary
      COG1196
      Location:311 → 825
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam15066
      Location:1 → 524
      CAGE1; Cancer-associated gene protein 1 family
      cl23943
      Location:447 → 527
      PCRF; PCRF domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086035.1 Reference GRCr8

      Range
      26995671..27033740
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006253808.5 → XP_006253870.1  cancer-associated gene 1 protein homolog isoform X1

      See identical proteins and their annotated locations for XP_006253870.1

      UniProtKB/Swiss-Prot
      Q66HB6
      UniProtKB/TrEMBL
      A6J7B4
      Conserved Domains (3) summary
      COG1196
      Location:311 → 825
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam15066
      Location:1 → 524
      CAGE1; Cancer-associated gene protein 1 family
      cl23943
      Location:447 → 527
      PCRF; PCRF domain

    2. XM_006253811.4 → XP_006253873.1  cancer-associated gene 1 protein homolog isoform X3

      See identical proteins and their annotated locations for XP_006253873.1

      UniProtKB/TrEMBL
      A0A8I5Y609
      Conserved Domains (2) summary
      pfam15066
      Location:1 → 524
      CAGE1; Cancer-associated gene protein 1 family
      cl23943
      Location:447 → 527
      PCRF; PCRF domain

    3. XM_006253810.5 → XP_006253872.1  cancer-associated gene 1 protein homolog isoform X3

      See identical proteins and their annotated locations for XP_006253872.1

      UniProtKB/TrEMBL
      A0A8I5Y609
      Related
      ENSRNOP00000077581.1, ENSRNOT00000111272.2
      Conserved Domains (2) summary
      pfam15066
      Location:1 → 524
      CAGE1; Cancer-associated gene protein 1 family
      cl23943
      Location:447 → 527
      PCRF; PCRF domain

    4. XM_006253809.5 → XP_006253871.1  cancer-associated gene 1 protein homolog isoform X2

      Related
      ENSRNOP00000101472.1, ENSRNOT00000169184.1
      Conserved Domains (3) summary
      COG1196
      Location:263 → 777
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam15066
      Location:3 → 476
      CAGE1; Cancer-associated gene protein 1 family
      cl23943
      Location:399 → 479
      PCRF; PCRF domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q66HB6.1 GenPept UniProtKB/Swiss-Prot:Q66HB6

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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