Tlcd1 TLC domain containing 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Tlcd1provided by RGD
Official Full Name: TLC domain containing 1provided by RGD
Primary source: RGD:1359195
See related: EnsemblRapid:ENSRNOG00000071015 AllianceGenome:RGD:1359195
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to be involved in several processes, including membrane assembly; phospholipid homeostasis; and regulation of membrane lipid distribution. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human TLCD1 (TLC domain containing 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Kidney (RPKM 124.2), Brain (RPKM 47.6) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 10q25

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	10	NC_086028.1 (63572541..63574574)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	10	NC_051345.1 (63074469..63076502)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	10	NC_005109.4 (65439104..65441140)

Chromosome 10 - NC_086028.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in membrane assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in membrane assembly	ISO Inferred from Sequence Orthology more info
involved_in phospholipid homeostasis	IBA Inferred from Biological aspect of Ancestor more info
involved_in phospholipid homeostasis	ISO Inferred from Sequence Orthology more info
involved_in plasma membrane organization	IBA Inferred from Biological aspect of Ancestor more info
involved_in plasma membrane organization	ISO Inferred from Sequence Orthology more info
involved_in regulation of membrane lipid distribution	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of membrane lipid distribution	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: TLC domain-containing protein 1

Names: calfacilitin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.