Eif1ad eukaryotic translation initiation factor 1A domain containing [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Eif1adprovided by RGD
Official Full Name: eukaryotic translation initiation factor 1A domain containingprovided by RGD
Primary source: RGD:1304686
See related: EnsemblRapid:ENSRNOG00000020463 AllianceGenome:RGD:1304686
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1304686
Summary: Predicted to enable RNA binding activity and translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Orthologous to human EIF1AD (eukaryotic translation initiation factor 1A domain containing). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Thymus (RPKM 118.5), Spleen (RPKM 97.4) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 1q43

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (212103715..212109015)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (202674362..202679662)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (220746387..220751687)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables translation initiation factor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in translational initiation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytosol	IEA Inferred from Electronic Annotation more info
located_in cytosol	ISO Inferred from Sequence Orthology more info
located_in intracellular membrane-bounded organelle	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: probable RNA-binding protein EIF1AD

Names: eukaryotic translation initiation factor 1A domain-containing protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001008305.1 → NP_001008306.1 probable RNA-binding protein EIF1AD

See identical proteins and their annotated locations for NP_001008306.1

Status: PROVISIONAL

Source sequence(s)

BC085818

UniProtKB/Swiss-Prot

Q5RKI6

UniProtKB/TrEMBL

A6HZ44

Related

ENSRNOP00000027752.3, ENSRNOT00000027753.7

Conserved Domains (1) summary

cd05792
Location:25 → 102

S1_eIF1AD_like; S1_eIF1AD_like: eukaryotic translation initiation factor 1A domain containing protein (eIF1AD)-like, S1-like RNA-binding domain. eIF1AD is also known as MGC11102 protein. Little is known about the function of eIF1AD. S1-like RNA-binding domains are found ...

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086019.1 Reference GRCr8

Range

212103715..212109015

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_039108337.2 → XP_038964265.1 probable RNA-binding protein EIF1AD isoform X1

UniProtKB/TrEMBL

A6HZ45

Conserved Domains (1) summary

cl09927
Location:1 → 50

S1_like; Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain. Both domains ...