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    Mrps31 mitochondrial ribosomal protein S31 [ Mus musculus (house mouse) ]

    Gene ID: 57312, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Mrps31provided by MGI
    Official Full Name
    mitochondrial ribosomal protein S31provided by MGI
    Primary source
    MGI:MGI:1913153
    See related
    Ensembl:ENSMUSG00000031533 AllianceGenome:MGI:1913153
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Imogen38; Imogen44; 1500002D03Rik
    Summary
    Predicted to enable protein domain specific binding activity. Located in mitochondrion. Is expressed in several structures, including brain; early conceptus; gonad; gut; and lung. Orthologous to human MRPS31 (mitochondrial ribosomal protein S31). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in placenta adult (RPKM 11.7), liver E14 (RPKM 7.7) and 26 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Mrps31 in Genome Data Viewer
    Location:
    8 A2; 8 11.28 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (22901356..22919685)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (22410449..22429669)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1810012K16 gene Neighboring gene STARR-positive B cell enhancer ABC_E6625 Neighboring gene predicted gene, 53406 Neighboring gene PDZ and LIM domain protein 5 pseudogene Neighboring gene STARR-seq mESC enhancer starr_20903 Neighboring gene STARR-seq mESC enhancer starr_20904 Neighboring gene predicted gene, 39140 Neighboring gene small integral membrane protein 19 Neighboring gene solute carrier family 20, member 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Imogen 38: a novel 38-kD islet mitochondrial autoantigen recognized by T cells from a newly diagnosed type 1 diabetic patient. Arden SD, et al. J Clin Invest, 1996 Jan 15. PMID 8567980, Free PMC Article
    2. Lmx1a and Lmx1b regulate mitochondrial functions and survival of adult midbrain dopaminergic neurons. Doucet-Beaupré H, et al. Proc Natl Acad Sci U S A, 2016 Jul 26. PMID 27407143, Free PMC Article
    3. Post-entrapment genome engineering: first exon size does not affect the expression of fusion transcripts generated by gene entrapment. Osipovich AB, et al. Genome Res, 2005 Mar. PMID 15741512, Free PMC Article
    4. Ribosome. The structure of the human mitochondrial ribosome. Amunts A, et al. Science, 2015 Apr 3. PMID 25838379, Free PMC Article
    5. Expression analysis of mammalian mitochondrial ribosomal protein genes. Cheong A, et al. Gene Expr Patterns, 2020 Dec. PMID 32987154, Free PMC Article

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein domain specific binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein domain specific binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial translation NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    part_of mitochondrial small ribosomal subunit ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    part_of mitochondrial small ribosomal subunit NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    small ribosomal subunit protein mS31
    Names
    28S ribosomal protein S31, mitochondrial
    MRP-S31
    S31mt
    imogen 38
    islet mitochondrial antigen, 38 kD

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_020560.2 → NP_065585.1  small ribosomal subunit protein mS31 precursor

      See identical proteins and their annotated locations for NP_065585.1

      Status: VALIDATED

      Source sequence(s)
      AK005110, BY237441
      Consensus CDS
      CCDS22176.1
      UniProtKB/Swiss-Prot
      Q3TSP5, Q61733, Q8VEH4, Q9D045
      Related
      ENSMUSP00000033934.4, ENSMUST00000033934.5
      Conserved Domains (1) summary
      pfam15433
      Location:85 → 377
      MRP-S31; Mitochondrial 28S ribosomal protein S31

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      22901356..22919685
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017312924.3 → XP_017168413.1  small ribosomal subunit protein mS31 isoform X1

      Conserved Domains (1) summary
      pfam15433
      Location:27 → 281
      MRP-S31; Mitochondrial 28S ribosomal protein S31

    RNA

    1. XR_003947320.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q61733.1 GenPept UniProtKB/Swiss-Prot:Q61733

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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