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    Dnajc16 DnaJ heat shock protein family (Hsp40) member C16 [ Mus musculus (house mouse) ]

    Gene ID: 214063, updated on 9-Dec-2024

    Summary

    Official Symbol
    Dnajc16provided by MGI
    Official Full Name
    DnaJ heat shock protein family (Hsp40) member C16provided by MGI
    Primary source
    MGI:MGI:2442146
    See related
    Ensembl:ENSMUSG00000040697 AllianceGenome:MGI:2442146
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    ERdj8; mKIAA0962; D030060M24; 2900037O03Rik; 4732437J24Rik
    Summary
    Predicted to be involved in regulation of autophagosome size. Predicted to be located in endoplasmic reticulum membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and sensory organ. Orthologous to human DNAJC16 (DnaJ heat shock protein family (Hsp40) member C16). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in ovary adult (RPKM 8.9), adrenal adult (RPKM 8.8) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Dnajc16 in Genome Data Viewer
    Location:
    4 D3; 4 74.75 cM
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (141487498..141518255, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (141761998..141790644, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 34863 Neighboring gene STARR-seq mESC enhancer starr_11931 Neighboring gene agmatinase Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:141346676-141346859 Neighboring gene STARR-positive B cell enhancer ABC_E1042 Neighboring gene caspase 9 Neighboring gene chymotrypsin-like elastase family, member 2A Neighboring gene chymotrypsin C Neighboring gene chymotrypsin C, opposite strand

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    involved_in regulation of autophagosome size ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of autophagosome size ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in endoplasmic reticulum membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endoplasmic reticulum membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    dnaJ homolog subfamily C member 16
    Names
    DnaJ (Hsp40) homolog, subfamily C, member 16
    ER-resident protein ERdj8
    endoplasmic reticulum DNA J domain-containing protein 8

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_172338.2NP_758841.1  dnaJ homolog subfamily C member 16 precursor

      See identical proteins and their annotated locations for NP_758841.1

      Status: PROVISIONAL

      Source sequence(s)
      AL928577
      Consensus CDS
      CCDS18882.1
      UniProtKB/Swiss-Prot
      Q80TN4, Q811G1, Q8BHI2
      Related
      ENSMUSP00000048714.5, ENSMUST00000038014.11
      Conserved Domains (2) summary
      COG0484
      Location:29135
      DnaJ; DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]
      cd02963
      Location:134243
      TRX_DnaJ; TRX domain, DnaJ domain containing protein family; composed of uncharacterized proteins of about 500-800 amino acids, containing an N-terminal DnaJ domain followed by one redox active TRX domain. DnaJ is a member of the 40 kDa heat-shock protein (Hsp40) ...

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      141487498..141518255 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036163946.1XP_036019839.1  dnaJ homolog subfamily C member 16 isoform X1

      UniProtKB/Swiss-Prot
      Q80TN4, Q811G1, Q8BHI2
      Conserved Domains (2) summary
      COG0484
      Location:29135
      DnaJ; DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]
      cd02963
      Location:134243
      TRX_DnaJ; TRX domain, DnaJ domain containing protein family; composed of uncharacterized proteins of about 500-800 amino acids, containing an N-terminal DnaJ domain followed by one redox active TRX domain. DnaJ is a member of the 40 kDa heat-shock protein (Hsp40) ...